Department of Biological Sciences

Faculty Edward J. Kennelly

E-mail address: kennelly@lehman.cuny.edu
Phone Number: 718-960-1105
Office: Davis Hall 132 (Lab: Davis Hall 119, 718.960.8914)
Rank: Professor
Degrees and Sources of Degrees: B.A., Colby Coll.; Ph.D., Washington Univ., in St. Louis

Research Interest

My research interest is in the area of biologically active phytochemicals. Plants produce a myriad of unusual compounds that are not used for primary metabolism, but are thought to be used for plant survival to various environmental challenges. The biological activities of these phytochemicals, also known as secondary products or natural products, have been harnessed by humans for millennia as medicines. The research conducted in my laboratory examines phytochemicals for novel biological actions. I am specifically interested in phytochemicals with antioxidant activity that may help to prevent cancer and cardiovascular disease.

The Phytochemistry Laboratory at Lehman College is a newly renovated facility in Davis Hall, room 119. It is fully equipped with instruments used for the identification and purification of natural products, including a gas chromatograph (HP 6890 with head space sampler), high performance liquid chromatographs (two Waters 2690 with 996 and one Waters 600 controller with 2487 dual wavelength detector), and a LC-MS (Finnigan Mat MS with Waters 2690 and 486 detector).

The Phytochemical Laboratory maintains collaborations with students of the CUNY Ph. D. Subprogram in Plant Sciences and Biochemistry, as well as with The New York Botanical Garden and The Richard and Hinda Rosenthal Center for Complementary & Alternative Medicine, Columbia University College of Physicians and Surgeons.

Field Research

  • Ethnobotanical expedition, Amazonian Ecuador, July-August, 1988 led by Dr. W.H. Lewis with Drs. M. Elvin-Lewis and M.C. Gnerre to study the use of plants in Jívaro culture.
  • Visit to southern Florida, June, 1993 and October, 1995, to collect plants with a sweet taste.
  • Visit to Southern China and Thailand, August, 1998, to study the use of plants in tropical Asia.
  • Visit to southern Florida, October, 1999 and October, 2000, to collect tropical fruits for antioxidant project.

Professional Memberships

Previous Work Experience

  • Postdoctoral Research Associate, Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago.
  • Visiting Assistant Professor, Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago.
  • Senior Staff Fellow, Office of Special Nutritionals, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration.

Other Experience

  • Manuscript reviewer for Phytochemical Analysis (John Wiley & Sons, Chichester, U.K.) and Journal of Natural Products (American Society of Pharmacognosy, Cincinnati, Ohio).
  • Basic Food and Drug Law Course (April 28 - May 2, 1997): U.S. Food and Drug Administration, Department of Health and Human Services, Washington, DC.
  • Science Council, Center for Food Safety and Applied Nutrition (1998): U.S. Food and Drug Administration, Department of Health and Human Services, Washington, DC.
  • Botanical Nomenclature Subcommittee (Spring, 1998): United States Pharmacopeia, Bethesda, MD.
  • United States Department of Agriculture, reviewer for National Research Initiative Competitive Grants Program (1999).
  • Hispanic Association of Colleges and Universities (HACU) Faculty Development Fellowship (1999).
  • Certified Research Administrator, Research Administrators Certification Council (1999).

Publications

direct search of publications through pubmed

2013

  • Borquez, J.; Kennelly, E.J.; Simirgiotis, M.J. 2013. Activity guided isolation of isoflavones and hyphenated HPLC-PDA-ESI-ToF-MS metabolome profiling of Azorella madreporica Clos. from northern Chile. Food Res. Int. 52: 288-297.
  • Einbond, L.S.; Mighty, J.; Kasiwazaki, R.; Figueroa, M.; Jalees, F.; Acuna, U.M.; Gendre, O.L.; Foster, D.A.; Kennelly, E.J.* 2013. Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric. Anticancer Agents Med. Chem. PMID:    23848206, in press.
  • Flores, G.; Dastmalchi, K.; Wu, S.B.; Whalen, K.; Dabo, A.J.; Reynertson, K.A.; Foronjy, R.F.; D Armiento, J.M.; Kennelly, E.J.* 2013. Phenolic-rich extract from the Costa Rican guava (Psidium friedrichsthalianum) pulp with antioxidant and anti-inflammatory activity. Potential for COPD therapy. Food Chem. 141: 889-895.
  • Huang, W.; Wu, S.-B.; Wang, Y.-L.; Guo, Z.-Y.; Kennelly, E.J.; Long, C.-L. 2013 Chemical constituents from Striga asiatica and its chemotaxonomic study. Biochem. Syst. Ecol. 48: 100-106.
  • Jiang, B.; Kronenberg, F.; Balick, M.J.; Kennelly, E.J.* 2013. Stability of black cohosh triterpene glycosides and polyphenols: potential clinical relevance. Phytomedicine, 20: 564-569.
  • Kronenberg, F.; Kennelly, E.J. 2013. Phytochemical identity and stability of herbal products: Challenges for clinical (Editorial). Maturitas, in press.
  • Lai, P.K.; Chan, J.Y.; Wu, S.B.; Cheng, L.; Ho, G.K.; Lau, C.P.; Kennelly, E.J.; Leung, P.C.; Fung, K.P.; Lau, C.B. 2013. Anti-inflammatory activities of an active fraction isolated from the root of Astragalus membranaceus in RAW 264.7 Macrophages. Phytother Res. DOI: 10.1002/ptr.5002.
  • Ma, C.; Dastmalchi, K.; Flores, G.; Wu, S.B.; Pedraza-Peñalosa, P.; Long, C.; Kennelly, E.J.* 2013. Antioxidant and metabolite profiling of North American and neotropical blueberries using LC-TOF-MS and multivariate analyses. J. Agric. Food Chem. 61: 3548-3559.
  • Ma, L.J.; Wang, Y.H.; Tang, G.H.; Wang, Y.L.; Ma, C.; Dastmalchi, K.; Kennelly, E.J.; Long, C.L. 2013. New monoterpene lactones from Actaea cimicifuga. Planta Med. 79: 308-311.
  • Petrova, V.I.; Kennelly, E.J. 2013. Blueberries: a "super fruit" complement to cereals. Cereal Foods World  58: 13-17.
  • Wu, S.B.; Long, C.; Kennelly, E.J.* 2013. Phytochemistry and health benefits of jaboticaba, an emerging fruit  crop from Brazil. Food Res. Int., 54: 148-159.
  • Wu, S.B.; Meyer, R.S.; Whitaker, B.D.; Litt, A.; Kennelly, E.J.* 2013 A new liquid chromatography-​mass spectrometry-​based strategy to integrate chemistry, morphology, and evolution of eggplant (Solanum) species. J. Chrom. A 1314: 154-172.
  • Wu, S.B.; Wu, J.; Yin, Z.; Zhang, J.; Long, C.; Kennelly, E.J.*; Zheng, S. 2013. Bioactive and marker compounds from two edible dark-colored Myrciaria fruits and the synthesis of jaboticabin. J. Agric. Food Chem. 61:4035-4043.
  • Simirgiotis, M.J.; Schmeda-Hirschmann, G.; Bórquez, J.; Kennelly, E.J. 2013. The Passiflora tripartita (Banana Passion) fruit: A source of bioactive flavonoid C-glycosides isolated by HSCCC and characterized by HPLC–DAD–ESI/MS/MS. Molecules. 18:1672-1692.

2012

  • Acuna, U.M.; Dastmalchi, K.; Basile, M.J.; Kennelly, E.J.* 2012. Quantitative high-performance liquid chromatography photo-diode array (HPLC-PDA) analysis of benzophenones and biflavonoids in eight Garcinia species. J. Food Compos. Anal. 25: 215-220.
  • Bradbury, L.M.T.; Shumskaya, M.; Tzfadia, O.; Wu, S.; Kennelly, E.J.; Wurtzel, E.T. 2012. Lycopene cyclase paralog CruP protects against reactive oxygen species in oxygenic photosynthetic organisms. Proc. Natl. Acad. Sci. U.S.A. 109: 10767-10768.
  • Dastmalchi, K.; Flores, G.; Wu, S.; Ma, C.; Dabo, A.J.; Whalen, K.; Reynertson, K.A.; Foronjy, R.F.; D'Armiento, J.M.; Kennelly, E.J.* 2012. Edible Myrciaria vexator fruits: Bioactive phenolics for potential COPD therapy. Bioorg. Med. Chem. 20: 4549-4555.
  • Flores, G.; Dastmalchi, K.; Dabo, A.J.; Whalen, K.; Pedraza-Penalosa, P.; Foronjy, R.F.; D'Armiento, J.M.; Kennelly, E.J.* 2012. Antioxidants of therapeutic relevance in COPD from the neotropical blueberry Anthopterus wardii. Food Chem. 131: 119-125.
  • Flores, G.; Dastmalchi, K.; Paulino, S.; Whalen, K.; Dabo, A.J.; Reynertson, K.A.; Foronjy, R.F.; D'Armiento, J.M.; Kennelly, E.J.* 2012. Anthocyanins from Eugenia brasiliensis edible fruits as potential therapeutics for COPD treatment. Food Chem. 1256-1262.
  • Huang, Q.; Bi, J.; Sun, Q.; Yang, F.; Wang, Y.; Tang, G.; Zhao, F.; Wang, H.; Xu, J.; Kennelly, E.J.; Long, C.; Yin, G. 2012. Bioactive isoquinoline alkaloids from Corydalis saxicola. Planta Med. 78: 65-70.
  • Nagler, M.; Kronenberg, F.; Kennelly, E.J.; Jiang, B.; Ma, C.H. 2012. The use of indicators for unobservable product qualities: Inferences based on consumer sorting. Int. J. Market. Stud. 4: 19-34.
  • Quinlan, R.F.; Shumskaya, M.; Bradbury, L.M.T.; Beltran, J.; Ma, C.; Kennelly, E.J.; Wurtzel, E.T. 2012. Synergistic interactions between carotene ring hydroxylases drive lutein formation in plant carotenoid biosynthesis. Plant Physiol. 160: 204-214.
  • Wu, S.B.; Dastmalchi, K.; Long, C.; Kennelly, E.J.* 2012. Metabolite profiling of jaboticaba (Myrciaria cauliflora) and other dark-colored fruit juices. J. Agric. Food Chem. 60: 7513-7525.
  • Wu, S.B.; Meyer, R.S.; Whitaker, B.D.; Litt, A.; Kennelly, E.J. 2012. Antioxidant glucosylated caffeoylquinic acid derivatives in the invasive tropical soda apple, Solanum viarum. J. Nat. Prod. 75: 2246-2250.
  • Yue, G.G.L.; Cheng, S.; Yu, H.; Xu, Z.; Lee, J.K.M.; Hon, P.; Lee, M.Y.H.; Kennelly, E.J.; Deng, G.; Yeung, S.K.; Cassileth, B.R.; Fung, K.; Leung, P.; Lau, C.B.S. 2012. The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells. J. Med. Food 15: 242-252.

2011

  • Dastmalchi, K.; Flores, G.; Petrova, V.; Pedraza-Penalosa, P.; Kennelly, E.J.* 2011. Edible neotropical blueberries: Antioxidant and compositional fingerprint analysis. J. Agric. Food Chem. 59: 3020-3026.
  • Hong, F.; Xiao, W.; Ragupathi, G.; Lau, C.B.S.; Leung, P.C.; Yeung, K.S.; George, C.; Cassileth, B.; Kennelly, E.J.; Livingston, P.O. 2011. The known immunologically active components of Astragalus account for only a small proportion of the immunological adjuvant activity when combined with conjugate vaccines. Planta Med. 77, 817-824.
  • Jiang, B.; Ma, C.; Motley, T.; Kronenberg, F.; Kennelly, E.J.* 2011. Phytochemical fingerprinting to thwart black cohosh adulteration: a 15 Actaea species analysis. Phytochem. Anal. 22, 339-351.
  • Kavalier, A.R.; Litt, A.; Ma, C.; Pitra, N.J.; Coles, M.C.; Kennelly, E.J.*; Matthews, P.D. 2011. Phytochemical and morphological characterization of Hop (Humulus lupulus L.) cones over five developmental stages using high performance liquid chromatography coupled to time-of-flight mass spectrometry, ultrahigh performance liquid chromatography photodiode array detection, and light microscopy techniques. J. Agric. Food Chem. 59, 4783-4793.
  • Kavalier, A.R.; Pitra, N.J.; Koelling, J.M.; Coles, M.C.; Kennelly, E.J.*; Matthews, P.D. 2011. Increase in cone biomass and terpenophenolics in hops (Humulus lupulus L.) by treatment with prohexadione-calcium. J. Agric. Food Chem. 59, 6720-6729.
  • Keller, A.C.; Ma, J.; Kavalier, A.; He, K.; Brillantes, A.B.; Kennelly, E.J.* 2011. Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro. Phytomedicine 19, 32-37.
  • Ma, C.; Dastmalchi, K.; Whitaker, B.D.; Kennelly, E.J. 2011. Two new antioxidant malonated caffeoylquinic acid isomers in fruits of wild eggplant relatives. J. Agric. Food Chem. 59, 9645-9651.
  • Ma, C.; Kavalier, A.R.; Jiang, B.; Kennelly, E.J.* 2011. Metabolic profiling of Actaea species extracts using high performance liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. J. Chromatogr. A 1218, 1461-1476.
  • Mazzola, E.P.; Parkinson, A.; Kennelly, E.J.; Coxon, B.; Einbond, L.S.; Freedberg, D.I. Utility of coupled-HSQC experiments in the intact structural elucidation of three complex saponins from Blighia sapida. Carbohydr. Res. 2011, 346, 759-768.
  • Nagler, M.; Kronenberg, F.; Kennelly, E.J.; Jiang, B.; 2011. Pricing for a credence good: An exploratory analysis. J. Prod. & Brand Manag. 20: 238-249
  • Xiao, W.; Motley, T.J.; Unachukwu, U.J.; Lau, C.B.S.; Jiang, B.; Hong, F.; Leung, P.; Wang, Q.; Livingston, P.O.; Cassileth, B.R.; Kennelly, E.J.* 2011. Chemical and genetic assessment of variability in commercial radix Astragali (Astragalus spp.) by ion trap LC-MS and nuclear ribosomal DNA barcoding sequence analyses. J. Agric. Food Chem. 59: 1548-1556.

2010

  • Acuna, U.M.; Figueroa, M.; Kavalier, A.; Jancovski, N.; Basile, M.J.; Kennelly, E.J.* Benzophenones and biflavonoids from Rheedia edulis. J. Nat. Prod. 2010, 73: 1775-1779.
  • Ahmed, S.; Unachukwu, U.; Stepp, J.R.; Peters, C.M.; Long, C.; Kennelly, E.J. 2010. Pu-erh tea tasting in Yunnan, China: Correlation of drinkers' perceptions to phytochemistry. J. Ethnopharmacol., 132: 176-185.
  • Fusco, D.; Liu, X.; Savage, C.; Taur, Y.; Xiao, W.; Kennelly, E.J.; Yuan, J.; Cassileth, B.; Salvatore, M.; Papanicolaou, G.A. 2010. Echinacea purpurea aerial extract alters course of influenza infection in mice. Vaccine 28: 3956-3962.
  • Huang, Y.; Jiang, B.; Nuntanakorn, P.; Kennelly, E.J.; Shord, S.; Lawal, T.O.; Soni, K.K.; Mahady, G.B. 2010. Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro. Curr. Drug Saf. 5: 118-124.
  • Lin, H.; Stanchina, E.; Zhou, X.K.; Hong, F.; Seidman, A.; Fornier, M.; Xiao, W.; Kennelly, E.J.; Wesa, K.; Cassileth, B.R.; Cunningham-Rundles, S. 2010. Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity. Cancer Immunol. Immunother. 59: 885-897.
  • Ma, C.; Whitaker, B.D.; Kennelly, E.J.* 2010. New 5-O-Caffeoylquinic acid derivatives in fruit of the wild eggplant relative Solanum viarum. J. Agric. Food Chem. 58, 11036-11042.
  • Ma, J.; Whittaker, P.; Keller, A.C.; Mazzola, E.P.; Pawar, R.S.; White, K.D.; Callahan, J.H.; Kennelly, E.J.; Krynitsky, A.J.; Rader, J.I. 2010. Cucurbitane-type triterpenoids from Momordica charantia. Planta Med. 76: 1758-1761.
  • Unachukwu, U.J.; Ahmed, S.; Kavalier, A.; Lyles, J.T.; Kennelly, E.J.* 2010. White and green teas (Camellia sinensis var. sinensis): variation in phenolic, methylxanthine, and antioxidant profiles. J. Food Sci. 75: C541-C548.
  • Yang, H.; Figueroa, M.; To, S.; Baggett, S.; Jiang, B.; Basile, M.J.; Weinstein, I.B.; Kennelly, E.J.* 2010. Benzophenones and biflavonoids from Garcinia livingstonei fruits. J. Agric. Food Chem. 58: 4749-4755.
  • Yue, G.G.; Chan, B.C.; Hon, P.; Kennelly, E.J.; Yeung, S.K.; Cassileth, B.R.; Fung, K.; Leung, P.; Lau, C.B. 2010. Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa. Int. J. Biol. Macromol. 47: 342-347.

2009

  • Jiang, B.; Reynertson, K.A.; Keller, A.C.; Einbond, L.S.; Bemis, D.L.; Weinstein, I.B.; Kronenberg, F.; Kennelly, E.J.* 2009. Extraction methods play a critical role in chemical profile and biological activities of black cohosh. Nat. Prod. Comm., 3: 1519-1532.
  • Keller, A.C.; Vandebroek, I.; Liu, Y.; Balick, M.J.; Kronenberg, F.; Kennelly, E.J.*; Brillantes, A.M. 2009. Costus spicatus tea failed to improve diabetic progression in C57BLKS/J db/db mice, a model of type 2 diabetes mellitus. J. Ethnopharmacol., 121: 248-254.

2008

  • Chan, B.Y.; Lau, K.S.; Jiang, B.; Kennelly, E.J.; Kronenberg, F.; Kung, A.W. 2008. Ethanolic extract of Actaea racemosa (black cohosh) potentiates bone nodule formation in MC3T3-E1 preosteoblast cells. Bone, 43:567-573.
  • Jiang, B.; Lyles, J.T.; Reynertson, K.A.; Kronenberg, F.; Kennelly, E.J.* 2008 Stability evaluation of selected polyphenols and triterpene glycosides in black cohosh. J. Agric. Food Chem., 56: 9510-9519.
  • Protiva, P.; Hopkins, M.E.; Baggett, S.; Yang, H.; Lipkin, M.; Holt, P.R.; Kennelly, E.J.; Weinstein, I.B. 2008. Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response. J. Cancer, 123: 687-694.
  • Reynertson, K.A.; Yang, H.; Jiang, B.; Basile, M.J.; Kennelly, E.J.* Quantitative analysis of antiradical phenolic constituents from fourteen edible Myrtaceae fruits. Food Chem., available electronically at: doi:10.1016/j.foodchem.2008.01.021.

2007

  • Einbond, L.S.; Shimizu, M.; Nuntanakorn, P.; Seter, C.; Cheng, R.; Jiang, B.; Kronenberg, F.; Kennelly, E.J.; Weinstein, I.B. 2007. Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells. Planta Med. 72: 1200-1206.
  • Einbond, L.S.; Su, T.; Wu, H.A.; Friedman, R.; Wang, X.; Jiang, B.; Hagan, T.; Kennelly, E.J.; Kronenberg, F.; Weinstein, I.B. 2007 Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth. Anticancer Res. 27: 697-712Ma, J.; Dey, M.; Yang, H.; Poulev, A.; Pouleva, R.; Dorn, R.; Lipsky, P.E.; Kennelly, E.J.; Raskin, I. 2007. Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii. Phytochemistry. 68: 1172-1178.
  • Nuntanakorn, P.; Jiang, B.; Yang, H.; Cervantes-Cervantes, M.; Kronenberg, F.; Kennelly, E.J.* 2007. Analysis of polyphenolic compounds and radical scavenging activity of four Actaea species. Phytochem. Anal. 18: 219-228
  • Simirgiotis, M.J.; Adachi, S.; To, S.; Yang, H.; Reynertson, K.A.; Basile, M.J.; Gil, R.R.; Weinstein, I.B.; Kennelly, E.J.* 2007. Cytotoxic chalcones and antioxidants from the fruits of Syzygium samarangense (wax jambu). Food Chem., 107: 813-819

2006

  • Jiang, B.; Kronenberg, F.; Balick, M.J.; Kennelly, E.J.* 2006. Analysis of formononetin from black cohosh (Actaea racemosa). Phytomedicine, 13: 477-486.
  • Jiang, B.; Kronenberg, F.; Nuntanakorn, P.; Qiu, M.-H.; Kennelly, E.J.* 2006. Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry. J. Agric. Food Chem. 54: 3242-3253. (Received national press coverage, including Science News).
  • Logendra, S.; Ribnicky, D.M.; Yang, H.; Poulev, A.; Ma, J.; Kennelly, E.J.; Raskin, I. 2006. Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry, 67: 1539-1546.
  • Luo, X.-D.; Wu, D.-G.; Cai, X.-H.; Kennelly, E.J. 2006. New antioxidant phenolic glycosides from Walsura yunnanensis. Chem. Biodivers. 3: 224-230
  • Nuntanakorn, P.; Jiang, B.; Einbond, L.; Yang, H.; Kronenberg, F.; Weinstein, I.B..; Kennelly, E.J.* 2006. Polyphenolic constituents from Actaea racemosa, J. Nat. Prod., 69: 314-318.
  • Reynertson, K.A.; Wallace, A.M.; Adachi, S.; Gil, R.R.; Yang, H.; Basile, M.J.; D’Armiento, J.; Weinstein, I.B.; Kennelly, E.J.* 2006. Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora). J. Nat. Prod. 69: 1228-1230.
  • Yang, H.; Jiang, B.; Reynertson, K.A.; Basile, M.J.; Kennelly, E.J.* 2006. Comparative analyses of bioactive mammea coumarins from seven parts of Mammea americana by HPLC-PDA with LC-MS. J. Agric. Food Chem. 54: 4114-4120.

2005

  • Baggett, S.; Protiva, P.; Mazzola, E.P.; Yang, H.; Ressler, E.T.; Basile, M.J. Weinstein, I.B.; Kennelly, E.J.* 2005.Bioactive benzophenones from Garcinia xanthochymus fruits. J. Nat. Prod., 68: 379-382.
  • Jiang , B.; Yang, H.; Nuntanakorn, P.; Balick, M.J.; Kronenberg, F.; Kennelly, E.J.* 2005. The value of plant collections in ethnopharmacology: a case study of an 85-year-old black cohosh (Actaea racemosa L.) sample. J. Ethnopharmacol., 96: 521-528. (Received national press coverage,)
  • Reynertson, K.A.; Balick, M.J.; Lee, R.; Raynor, W.; Pelep, Y.; Kennelly, E.J.* 2005. A traditional method of Cinnamomum carolinense preparation eliminates safrole from a therapeutic Pohnpeian tea. J. Ethnopharmacol., 102: 269-274.
  • Yang, H.; Protiva, P.; Gil, R.; Jiang, B.; Baggett, S.; Weinstein, I.B.; Kennelly, E.J.* 2005. Antioxidant and cytotoxic isoprenylated courmarins from Mammea americana. Planta Med., 71: 852-860.

2004

  • Einbond, L.; Shimazu, M.; Xiao, D.-H.; Nuntanakorn, P.; Lim, J.T.E.; Suzui, M.; Seter, TC.; Pertel, T.; Kennelly, E.J.; Kronenberg, F.; Weinstein, I.B. 2004. Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells. Breast Canc. Res. Treat., 83: 221-231.
  • Ma, J.; Yang, H.; Basile, M.J.; Kennelly, E.J.* 2004. Analysis of polyphenolic antioxidants from the fruits of three Pouteria species by selected ion monitoring liquid chromatography-mass spectrometry. J. Agric. Food Chem., 52: 5873-5878.

2003

  • Einbond, L.; Reynertson, K.A.; Luo, X.-D.; Basile, M.J.; Kennelly, E.J.* 2003. Anthocyanin antioxidants from edible fruits. Food Chem., 84: 23-28
  • Lupu, R.; Mehmi I.; Atlas, E.; Tsai, M.-S.; Pisha, E.; Oketch-Rabah, H.A.; Nuntanakorn, P.; Kennelly, E.J.; Kronenberg F. 2003. Black cohosh, a menopausal remedy, does not have estrogenic activity and does not promote breast cancer cell growth. Int. J. Oncol. 23: 1407-1412.
  • Ma, J.; Luo, X.-D.; Protiva, P.; Yang, H.; Ma, C.; Basile, M.J.; Weinstein, I.B.; Kennelly, E.J.* 2003. Bioactive novel polyphenols from the fruit of Manilkara zapota (sapodilla). J. Nat. Prod., 66: 983-986.
  • Yang, H.; Protiva, P.; Cui, B.; Ma, C.; Baggett, S.; Hequet, V.; Mori, S.; Weinstein, I.B.; Kennelly, E.J.* 2003. New bioactive polyphenols from Theobroma grandiflorum (“cupuaçu”). J. Nat. Prod., 66: 1501-1504.

2002

  • Luo, X.-D.; Basile, M.J.; Kennelly, E.J.* 2002. Polyphenolic antioxidants from the fruits of Chrysophyllum cainito (Star Apple). J. Agric. Food Chem., 50: 1379-1382.
  • Kennelly, E.J.*; Baggett, S.; Nuntanakorn, P.; Ososki, A.L.; Mori, S.A.; Duke, J.; Coleton, M.; Kronenberg, F. 2002. Analysis of thirteen populations of black cohosh for formononetin. Phytomedicine 9: 461-467.
  • Muño-Acuña, U.; Atha, D.; Ma, J.; Nee, M.; Kennelly, E.J.* 2002. Antioxidant capacities of ten edible North American fruits. Phytother. Res., 16: 63-65.
  • Opler, A.; Mizell, R.; Robert, A.; Cervantes-Cervantes, M.; Kincaid, D.; Kennelly, E.J. 2002. Use of brine shrimp assay to study herbal teas in the classroom. Am. Bio. Teach. 64: 516-524.

1999

  • Kennelly, E.J.*; Mazzola, E.P.; Flynn, T.J.; McCloud, T.G.; Danford, D.E.; Betz, J.M. 1999. Detecting potential teratogenic alkaloids from blue cohosh rhizomes using an in vitro rat embryo culture. J. Nat. Prod., 62: 1385-1389.

1998

  • Kinghorn, A.D.; Kaneda, N.; Baek, N.-I.; Kennelly, E.J.; Soejarto, D.D. 1998. Noncariogenic intense natural sweeteners. Med. Res. Rev., 18: 347-360.
  • Chang, L.-C.;Bhat, K.P.L.; Pisha, E.; Kennelly, E.J.; Fong, H.H.S.; Pezzuto, J.M.; Kinghorn, A.D. 1998. Activity-guided isolation of steroidal alkaloid antiestrogen-binding site inhibitors from Pachysandra procumbens. J. Nat. Prod., 61: 1257 -1262.

1997

  • Chung, M.-S.; Kim, N.-C.; Long, L.; Shamon, L.; Ahmad, W.-Y.; Sagrero-Nieves, L.; Kardono, L.B.S.; Kennelly, E.J.; Pezzuto, J.M.; Soejarto, D.D.; Kinghorn, A.D. 1997. Dereplication of saccharide and polyol constituents of candidate sweet-tasting plants: Isolation of the sesquiterpene glycoside mukurozioside IIb as a sweet principle of Sapindus rarak. Phytochem. Anal., 8: 49-54.
  • Shao, Y.; Poobrasert, O.; Kennelly, E.J.; Chin, C.-K.; Ho, C.-T.; Huang, M.-T.; Garrison, S.A.; Cordell, G.A. 1997. Steroidal saponins from Asparagus officinalis and their antitumor activity. Planta Med., 63: 258-260.
  • Kennelly, E.J.; Gerhäuser, C.; Graham, J.G.; Beecher, C.W.W.; Pezzuto, J.M.; Kinghorn, A.D. 1997. Induction of quinone reductase by withanolides isolated from Physalis philadelphica (tomatillos). J. Agric. Food Chem., 45: 3771-3777.
  • Shin, K.H.; Woo, W.S.; Lim, S.S.; Shrim, C.S.; Chung, H.S.; Kennelly, E.J.; Kinghorn, A.D. 1997. Elgonica-dimers A and B, Two potent alcohol metabolism inhibitory constituents of Aloe arborescens. J. Nat. Prod., 60: 1180 ‑1182.

1996

  • Kennelly, E.J.; Cai, L.; Kim, N.-C.; Kinghorn, A.D. 1996. Abrusoside E, A further sweet-tasting cycloartane glycoside from the leaves of Abrus precatorius. Phytochemistry, 41: 1381-1383.
  • Kennelly, E.J.; Suttisri, R.; Kinghorn, A.D. 1996. Novel sweet-tasting saponins of the cycloartane, oleanane, secodammarane, and steroidal types. In Saponins: Chemistry and Biological Activity. G.R. Waller and K. Yamaski, Eds. Plenum Publishing Corp., New York, pp. 13-24.

1995

  • Kennelly, E.J.; Cai, L.; Long, L.; Shamon, L.; Zaw, K.; Zhou, B.-N.; Pezzuto, J.M.; Kinghorn, A.D. 1995. Novel highly sweet secodammarane glycosides from Pterocarya paliurus. J. Agric. Food Chem., 43: 2602-2607.
  • Kinghorn, A.D.; Kennelly, E.J. 1995. Discovery of highly sweet compounds from natural sources. J. Chem. Educ., 72: 676-680.

1994

  • Baek, N.-I.; Kennelly, E.J.; Kardono, L.B.S.; Tsauri, S.; Padmawinata, K.; Soejarto, D.D.; Kinghorn, A.D. 1994. Flavonoids and a proanthocyanidin from the rhizomes of Selliguea feei. Phytochemistry, 36: 513-518.
  • Nishizawa, M.; Yamada, H.; Yamaguchi, Y.; Hatakeyama, S.; Lee, I.-S.; Kennelly, E.J.; Kim, J.; Kinghorn, A.D. 1994. Structure revision of polypodoside A: Major sweet principle of Polypodium glycyrrhiza. Chem. Lett., 1555-1558, 1979.

1993

  • Lewis, W. H.; Kennelly, E.J.; Bass, G.N.; Wedner, H.J.; Elvin-Lewis, M.P.; Fast, F.D. 1991. Ritualistic use of the holly Ilex guayusa by Amazonian Jívaro Indians. J. Ethnopharmacol., 33: 25-30.
  • Kennelly, E.J.; Lewis, W.H.; Winter, R.E.K.; Johnson, S.; Elvin-Lewis, M.P.; Gossling, J. 1993. Triterpenoid saponins from Gouania lupuloides. J. Nat. Prod., 56: 402-410.

1991

  • Kohl, D.H.; Kennelly, E.J.; Zhu, Y.; Schubert, K.R.; Shearer, G. 1991. Proline accumulation, nitrogenase (C2H2 reducing) activity, and activities of enzymes related to proline metabolism in water stressed nodules. J. Exp. Bot., 42: 831-837.

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